Abstract

• Lycopersicon esculentum Mill. belongs to the family Solanaceae. It is known as the kha yan gyin in Myanmar. Two cultivars of Lycopersicon esculentum Mill., cv. local and cv. 909 (Taiwan) were collected from Moe Kaung village, Sintgaing Township, Mandalay Region. Morphological and histological studies on two cultivars of Lycopersicon esculentum Mill. were carried out, to get their correct identification. Determination of nutritional values of two cultivars such as water, carbohydrate, crude fiber, proteins and fat were also investigated. The acute toxicity study of ethanol extracts of two cultivars on albino mice were performed. The lethal effect was not observed even use of maximum does of 2500 mg/kg. The hypoglycemic effect of ethanol extracts from two cultivars on adrenaline induced hypoglycemic albino mice were tested. These two cultivars show more reduction of hypoglycemic activity than standard drug, glibenclamide. The property of reduction of blood glucose concentration of ethanol extract cv. local and cv. 909(Taiwan) and glibenclamide were compared. From the comparison, ethanol extract of cv. local can reduce hyperglycemia better than that of cv. 909(Taiwan).