Abstract

• This research deals with the study on nutritional value and antidiabetic activity of seed of Swietenia macrophylla King (Mahogany). Mahogany fruits were collected from Hinthada University campus. In the preliminary phytochemical investigation, it was found that alkaloids, phenolic compounds, flavonoids, steroids, terpenoids, tannins, saponins, carbohydrates, reducing sugars, glycosides and trace amount of cyanogenic glycosides were present in the seed whereas α- amino acid was not detected. Determination of the nutritional values of the seed provided 24.03 % of crude fat, 14.70 % of protein, 13.03 % of dietary fiber, 8.45 % of moisture, 3.15 % of ash and 36.64 % of carbohydrate. According to ED-XRF analysis, the elemental composition of the seed was found to be potassium (1.145 %), phosphorus (0.526 %), sulphur (0.227 %), calcium (0.190 %), iron (0.004 %) and minor components (0.002 %) of Mn, Zn and Cu. After that, the antidiabetic activity of the seed was evaluated by alpha amylase inhibition assay method. IC50 values of the extracts were found to be 0.069 mg/mL of ethanol, 0.096 mg/mL of ethyl acetate and 0.168 mg/mL of water extracts.