Abstract

• The main aim of the present work is to study phytochemical screening, nutritive values and some biological activities of seed (kernel) of Z. mauritiana Lam. (Zee). For preliminary phytochemical test, alkaloids, α-amino acids, carbohydrates, flavonoids, glycosides, phenolic compounds, saponins, starch, tannins, steroids and terpenoids were determined but cyanogenic glycosides and reducing sugars were absent in the Zee seed. The nutritive values such as crude proteins, ash, fibers, moisture, carbohydrates and fats were found to be 39.91 %, 4.27 %, 15.29 %, 7.23 %, 12.97 % and 27.56 % respectively. Moreover, methanol, ethyl acetate, ethanol extracts were revealed antimicrobial activity (inhibition zone diameters = 1118 mm) against all tested microorganisms while pet-ether and watery extracts did not show activity. Ethanol extract was possessed potent antimicrobial activity than methanol and ethyl acetate extracts. Antiproliferative activity of ethanol and watery extracts of Z. mauritiana Lam. against Hela (Cervix) and A 549 (Lung) cancer cell lines were screened by MTT assay. The IC50 value of watery extract was found to be 170.36 g/mL against cervix cancer. Both ethanol and watery extracts did not show anti-inflammatory activity and cytotoxicity effect.