Abstract

• In the present research, soil samples were collected from three different places of Katha Township, Sagaing Region, during July 2019 and isolated them by the serial dilution method. The media used for the isolation includes Blakeslee’s Malt Extract Agar (BMEA) medium and Potato Dextrose Agar (PDA) medium, incubated for 3-7 days at room temperature. Pure colonies were preserved into slant culture containing PDA medium. Twenty fungal strains were obtained. The surface colours of all isolated fungi are white, black, blue, brown, cream, green, dark green, pale yellow, pink, yellow and greenish yellow and their reserve colours are brown, cream, pale yellow, pink, red and yellow. In the colony morphology, the isolated fungi are medium and large in size. The margin of isolated fungi are entire, undulate, filamentous and the elevation of isolated fungi are flat, umbonate and raised. In the form, isolated fungi are irregular, circular and filamentous. Furthermore, the antimicrobial activity of all fungal strains were tested by agar well diffusion method on eight test organisms. Among them, four fungal strains showed the antimicrobial activity on all test organisms. Especially, TM- 14 and 16 showed the highest antimicrobial activity. These findings suggested that the soil fungi may be utilized for screening of the antimicrobial substances and to treat the diseases caused by pathogenic microorganisms.