Abstract

• This research work has focused on the elucidation of chemical constituents and some biological activities of the fresh rhizome of C. aeruginosa Roxb. The phytochemical screening of C. aeruginosa Roxb. powder reveals the presence of several compounds. The main phytochemical constituents include alkaloids, carbohydrates, amino acid, flavonoids, phenolic compounds, glycosides, reducing sugars, starch, steroids, terpenoids, and tannins. However, cyanogenic glycoside and saponin were not detected at the assay conditions. In the screening of the antioxidant activity, ethanol extract (IC50= 1.56 g/mL) was found to be more potent than watery extract (IC50 =3.95 g/mL). The total phenol contents (TPC) of ethanol extract (52.31 ±8.70 g GAE/mg) was found to be higher than watery extract (16.92 ± 0.20 g GAE/mg).The antimicrobial activities of (PE, EtOAc, EtOH and water) extracts from C. aeruginosa Roxb. sample were determined against seven strains of microorganisms (. subtilis, . aureus, P. aeruginosa, . pumilus, C. albicans, E.coli and . tumefaciens) by agar well diffusion method. The highest antimicrobial activity was observed in EtOH extract whereas H2O extract showed minimum activity. Antitumor activity was carried out with EtOAc and EtOH extracts by PCG test. From this experiment, both extracts were found to prevent the tumor formation with the dose of 0.1 and 0.15 mg/disc. The rhizome of C.aeruginosa Roxb.could be applied not only as the local health remedy to the local indigenous but also for the treatment of some bacterial plant pathogen and diseases in agriculture of Myanmar.