Abstract

• This research is concerned ith the chemical investigation and some dermatological activity of . ingle Thee bar.  antistaphylococcal activities of petether, ethanol and ater crude extracts ere evaluated by investigating the healing potential on  induced excision type cutaneous ounds. ll extracts too days to heal ound. o significant difference on ound healing effect beteen different doses of mgday as observed. Control group needed days to heal ound. in hitening activity as determined by using a modification of Imoaa Method. In this study, guinea pig as chosen as the experimental animal because its sin histologically and biochemically is similar to the human sin. Petether andethanol extracts, and oic acid control ere topically applied on sun rays induced hyperpigmented sin of guinea pigs for three successive ees. fter ees, petether and ethanol extracts treated portion ere found to be hiter than that of untreated hyperpigmented sin. The hitening effect of petether and ethanol extracts ere found to be similar, hoever, loer than that of oic acid. In chemical investigation, to compounds ere isolated from chloroform extract of  Thee bar. These ere Compound I ergapten . yield, mp.C and Compound II marmesin . yield, mp. C.These compounds have been identified by spectroscopic measurement , TIR, MR and C MR.