Abstract

• -hingala) and Eleusine indica L. (Sinngo-inyet) were selected for some bioactivity studies. Antioxidant activity of crude extracts was investigated by using DPPH radical scavenging activity assay. According to the observed data, ethanol extract of Sinngo-myet (IC50 = 86.14 µg/mL) showed similar activity with that of Taw-hingala (IC50 = 86.18 µg/mL). The cytotoxicity of 70 % ethanol and watery extracts of Taw-hingala and Sinngo-myet was studied by brine shrimp cytotoxicity bioassay. Among the four crude extracts (ethanol and watery extracts from two samples), only ethanol extract of Taw-hingala showed strong cytotoxic effect on brine shrimp at LD50= 1.50 µg/mL but the other crude extracts did not exhibit their cytotoxic effect up to the optimum dose of 1000 µg/mL. Antitumor activity of ethanol and watery extracts of Taw-hingala and Sinngo-myet was also tested on tumor produced bacterium using PCG (Potato Grown Gall) test. From this experiment, the text extracts from all samples were significantly found to inhibit the formation of tumor in the dose of 0.062 g/disc. From the result of screening of antiproliferative activity, it was observed that methanol extracts of the whole plant of Taw-hingala and Sinngo-myet showed mild antiproliferative activity of IC50 value at > 100 µg/mL for lung cancer, cervix cancer, breast cancer, normal human fibroblast, liver cancer, pancreatic cancer and pancreas ductal adenocarcinoma respectively