Abstract

• In this research, the phytochemical analysis and antimicrobial activities of the flowers and seeds of Gymnanthemum amygdalinum Walp. were studied. It belongs to the family Asteraceae. The plants were collected from Kyaing Tong Township, Eastern Shan State. English name is bitter leaf plant and Shan name is Sa paung Lone. These investigations had been carried out by (Harbone, 1973 and Trease and Evans, 2002) in the Pharmaceutical Research Department of Ministry of Industry, Yangon Region. Alkaloid, carbohydrate, glycoside, phenolic compound, α-amino acid, saponin, tannin, flavonoids, steroids, terpenoids, reducing sugar and starch were observed in the flowers of studied plant. Tannin and cyanogenic glycoside did not observed in the seeds of this plant. For antimicrobial activities, the different extracts of flowers and seeds of G. amygdalinum were applied on some different microorganisms. The antimicrobial activity was done by using agar well diffusion method. Partially active and active were observed on studied microorganisms. The highest inhibition zones (15 mm- 20 mm) were found in ethanol extract of flowers and petroleum ether extracts of seeds. These results can be used for further pharmaceutical studied.