Abstract

• In this research work, one of Myanmar medicinal plants namely, Pittosporum napaulensis (DC.) (Mayanin) was first chosen for chemical investigation. Phytochemical screening of the selected sample was carried out by using standard method. The sample contains alkaloids, flavonoids, glycosides, phenolic compounds, polyphenols, saponins, terpenes and tannins. Moreover, the antibacterial activity of various extracts of sample were tested by using Agar well diffusion method on six selected test organisms. According to the results, the n-hexane extract showed the highest activity against Salmonella typhi. Ethyl acetate extract and water extract were showed the highest activity on Micrococcus luteus and Salmonella typhi. Furthermore, antioxidant activity of various crude extracts of sample were carried out by 1,1-diphenyl-2-picrylhydrazyl (DPPH) essay method using UV-Visible spectrophotometer. According to the result, the antioxidant activity of ethyl acetate extract was more effective than n-hexane extract. Moreover, the results of anti inflammatory for the treatment groups at different dosages indicate varying degrees of inhibition: 40 % at 0.75 mg/ear, 56 % at 0.59 mg/ear, 62 % at 0.45 mg/ear and 0.36 mg/ear.